Addiction to illicit substances: an increasing phenomenon

Drug addiction is the repetitive and compulsive will to consume a substance (illicit or not) despite efforts to quit this habit. An individuals who suffers from drug addiction will experience a craving sensation when not being able to usually consume the substance he is addicted to, even though its consumption is not vital.

Addiction is characterized by the repetition of consumption behavior despite efforts to quit the addictive habit, and knowing fully the potential harmful consequences of this habit.

The addicted individual’s dependency to a specific substance can be both physical and psychological.

Neuropsychological studies have shown the essential connection between a dysfunctioning reward mechanism and addiction.

Addiction models

in vitro models

  • Neuroservice, our member expert in cell and slice electrophysiology, proposes slice electrophysiological assays on addiction models

in vivo models

  • OptoPath, our expert platform for rodent models of neurological disorders, proposes several tests to evaluate the addictive risk of new psychoactive compounds , as well as the anti-addiction potential of new compounds
  • Key-Obs, our expert in behavioural models of neurological disorders, offers several behavioural addiction models (withdrawal, relapse…)

Are you currently working on compounds targeting anxiety, stress or PTSD?

Please contact us for any additional information and we will gladly come back to you. We can also set up a dedicated meeting between you and our experts to discuss our CRO services and your research needs.

Véronique DEROCHE, PhD
Addiction models
OPTOPATH
Bruno BUISSON, PhD
Co-Founder, President & CSO
NEUROSERVICES-ALLIANCE
& NEUROSERVICE
Bob PETROSKI, PhD
Scientific liaison
NEUROSERVICES-ALLIANCE
Jeffrey HUBBARD, PhD
Head of Patch-Clamp laboratory
NEUROSERVICE
Jean-Charles BIZOT, PhD
CEO & Behavioral Pharmacologist
KEY-OBS
Fabrice TROVERO,PhD
GM & Behavioral Pharmacologist
KEY-OBS