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Key-Obs is a preclinical Contract Research Organization (CRO) specialized in Central Nervous System diseases.

For more than 20 years, Key-Obs offers in vivo models to evaluate drug efficacy in CNS diseases and behavioral tests dedicated to the phenotyping of transgenic mice.

In vivo models and screening assays

Key-Obs offers in vivo models and screening assays in the fields of psychiatry (schizophrenia, depression, anxiety), cognition, neurodegenerative diseases (Alzheimer disease, Parkinson disease), juvenile diseases (ADHD, autism), rare diseases (Huntington disease, CMT), ALS, as well as genotyping/phenotyping of various transgenic rodents

Neuropharmacology – Behavior analysis in rodents - models of CNS diseases

Available assays

  • Large portfolio of behavioral and functional observations in rodents for pharmacological studies in CNS diseases
  • Robust background & Quality: A wide database on several animal strains & various reference compounds
  • Dose response protocols
  • Options: plasma and/or brain samples for subsequent analysis (e.g. PK/PD)

Case study

Psychiatric disorders
In Vivo compound screening in Psychiatry

Learn more

Key-Obs Experts

GM & Behavioral Pharmacologist
Jean-Charles BIZOT, PhD
CEO & Behavioral Pharmacologist