CNS Safety pharmacology: why?

Safety pharmacology is a critical component of the drug discovery process, as it helps to identify potential side effects on cognitive functions of drugs entering the Central Nervous System early on in development. This allows for necessary adjustments to be made before the drug enters clinical trials, reducing the chances of costly and time-consuming delays or setbacks.

Evaluating the CNS Safety of drugs is essential to ensure that they are safe and effective for human use. Additionally, the FDA and other regulatory bodies require thorough evaluation of CNS Safety as part of the drug approval process. It is therefore crucial that drug development teams prioritize and incorporate CNS Safety pharmacology evaluations early on in the drug discovery process.

CNS Safety assays

in vitro assays

  • Our cell electrophysiology and brain slice electrophysiology platforms propose:
    • Safety tests on rodent brain and spinal cord slices
    • Safety tests on human iPSC-derived neurons
  • AnaBios, our preferred partner expert in human tissue samples & services for CNS drug discovery, provides:
    • Safety tests on human sensory neurons

 

Bruno Buisson, PhD
Co-Founder, President & CSO
Bob Petroski, PhD
CSO in vitro cell
electrophysiology
Andre GHETTI, PhD
CEO
ANABIOS
Najah ABI-GERGES, PhD
VP of R&D
ANABIOS
Celia BELLINE, MSc
CEO, Hearing Disorders expert
CILCARE
Gaƫlle Naert, PhD
COO, Hearing Disorders expert
CILCARE
Marie-Pierre PASDELOU, Pharm.D
CDO, Hearing Disorders expert
CILCARE
Sylvie PUCHEU, PhD
CSO, Hearing Disorders expert
CILCARE