Located in San Diego, California, AnaBios aims to establish the safety and efficacy of novel compounds through its advanced, human-focused translational technologies.

AnaBios’ human tissue-based methods provide a very powerful strategy that combines the benefit of in vivo measurements (in animals) with the ability to generate human data (ex vivo) to overcome the challenges of cross-species translation.

AnaBios’s objective is to generate human ex vivo data for the biopharmaceutical industry:

  • Target identification, MOA investigation, compound profiling on human tissue
  • Tests in hDRG for PAIN drug discovery
  • Neurotoxicity test in hDRG
  • Safety pharmacology assays with human cardiomyocytes and tissue preparations


AnaBios offers early human insights into the drug development process and is redefining “First-in-Human” studies. Leveraging extensive knowledge of human tissue procurement and strategic utilization, AnaBios provides the unprecedented opportunity to de-risk drug development programs by assessing the safety and efficacy of drugs directly in human tissues and cells at the preclinical stage.

Human tissue-based assays

Human dorsal root ganglia (hDRG) cultured neurons from Normal and Chronic Pain Donors

Techniques (Assays in isolated adult hDRG neurons):

–        Electrophysiology – current clamp

–        Calcium imaging with electrical field stimulation

Case study

Clone Cardiac Ion Channel Data

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Case Study

Predicting Heart Rate Effects on Ex Vivo Human Sa Node

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AnaBios Experts

CEO of AnaBios
Founding Partner and Chief Business & Corporate Development Officer of AnaBios.
AnaBios R&D Vice President

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