Schizophrenia: chronic mental illness

Schizophrenia is a long-term mental condition belonging to the psychosis disease conditions. It causes a wide range of psychological symptoms: paranoia, dementia, hallucinations, delusions… Early diagnosis by a mental health care professional allow for a better medical treatment.

Even though the exact cause of schizophrenia remains unknown, it is believed that a combination of genetic and environmental factors can trigger the disease. Existing medical treatments include antipshychotic medicines as well as CBT (Cognitive Behavioural Therapy). Treating schizophrenia early usually allows patient to recover fully, but certain patients will experience relapse episodes.

Current antipsychotics work by blocking the effect of chemical dopamine on the brain, thus helping reduce the anxiety and aggression feeling experienced by patients.

Schizophrenia assays & models

in vitro models

  • Our member Neuroservice, CNS expert in in vitro cell and slice electrophysiology, provides:
    • Electrophysiological assays on slice from schizophrenic rodent models

in vivo models

  • Our member Key-Obs, expert in models and behavioural assays of neurological disorders, provides behavioural investigations of Tg or pharmacological schizophrenic rodent models

Are you currently working on compounds targeting Schizophrenia?

Please contact us for any additional information and we will gladly come back to you. We can also set up a dedicated meeting between you and our experts to discuss our CRO services and your research needs.

Jeffrey HUBBARD, PhD
Head of Patch-Clamp laboratory
NEUROSERVICE
Bruno BUISSON, PhD
Co-Founder, President & CSO
NEUROSERVICES-ALLIANCE
& NEUROSERVICE
Jean-Charles BIZOT, PhD
CEO & Behavioral Pharmacologist
KEY-OBS
Fabrice TROVERO,PhD
GM & Behavioral Pharmacologist
KEY-OBS